New research on how Marek’s may affect immune system

Researchers from Freie Universität Berlin in Germany explained that MDV infection starts with the inhalation of infectious dust. Mononuclear phagocytes transfer the virus to lymphoid organs, such as the spleen, thymus, and bursa, where the virus lytically replicates in lymphocytes. MDV can establish latency in infected T cells. Latently and/or lytically infected T cells transport the virus to the skin and feather follicle epithelia (FFE), where cell free MDV is generated. In addition, MDV can transform latently infected T cells, resulting in deadly lymphomas.

Marek’s disease virus (MDV) in chickens is estimated to cost the global poultry industry up to USD 2 billion each year. In Asia, economic losses are spiking despite the wide use of vaccines.

In the early stages of disease, MDV directly affects the chicken’s immune system and prevents it function...

Sign in  as a member, or Join our Community  for free to unlock the full article.

Managing Editor and Editor of Asian Poultry Magazine, Jakarta, Indonesia. Using Rabobank’s 2023 poultry review, he writes about ‘Keeping chicken meat affordable’ despite the challenging economic climate, diseases, and lower purchasing power.